Defying Gravity is a 2009 multinational-coproduction drama about eight astronauts aboard the spaceship "Antares," on a six-year exploratory "grand tour" of the solar system in 2052. The series is an uneasy hybrid of fairly realistic SF and bad soap opera, with a dash of conspiratorial paranoia thrown in (some kind of mysterious inhuman entity, "Beta," having been surreptitiously placed on board by the authorities, is apparently manipulating everyone.) It's also the first space-themed series on a US big-three network in 20 or so years; critics have not been impressed.

The space agency in charge is the ISO ("International Space Organization") a carbon copy of NASA in almost every respect, but presumably denationalized to better appeal to international audiences.
Eugene Ipavec, 22 August 2009